Lecture 24 – Designing Future Products with Reduced Toxicity
This lecture continues to explore different approaches to hazard minimization by changing molecular design. After several practical examples and a case study, students will learn about current methods that scientists use to assess chemical toxicity on a large scale. In vivo and In vitro studies are discussed.
Lesson download includes:
Lesson Plan 24: Designing Future Products with Reduced Toxicity
PowerPoint Presentation 24: Designing Future Products with Reduced Toxicity
Content Preview: Approaches to hazard minimization through molecular design, Case study: Codexis, Alternatives to animal testing, QSAR-Quantitative Structure Activity Relationship, The nexus of chemistry and toxicology, Sources of high throughput data
Homework 6: Toxicology with examples and answer key
Class Exercise: Using ProTox Class, Glutathione as a Tool, Crossroads of Computation
Reading: Selection of Chemical Alternatives
Download Lesson
